Dosing Schedules for Pneumococcal Conjugate Vaccine
نویسندگان
چکیده
منابع مشابه
Dosing Schedules for Pneumococcal Conjugate Vaccine
Since second generation pneumococcal conjugate vaccines (PCVs) targeting 10 and 13 serotypes became available in 2010, the number of national policy makers considering these vaccines has steadily increased. An important consideration for a national immunization program is the timing and number of doses-the schedule-that will best prevent disease in the population. Data on disease epidemiology a...
متن کاملSystematic Review of the Effect of Pneumococcal Conjugate Vaccine Dosing Schedules on Vaccine-type Nasopharyngeal Carriage
BACKGROUND Pneumococcal conjugate vaccines (PCV) reduce nasopharyngeal carriage of vaccine type (VT) pneumococci, an important driver of vaccine programs' overall benefits. The dosing schedule that best reduces carriage is unclear. METHODS We performed a systematic review of English language publications from 1994 to 2010 (supplemented post hoc with studies from 2011) reporting PCV effects on...
متن کاملMethods for a Systematic Review of Pneumococcal Conjugate Vaccine Dosing Schedules
BACKGROUND Streptococcus pneumoniae causes a considerable amount of morbidity and mortality in children <5. However, pneumococcal conjugate vaccines (PCVs) can prevent much of this burden. Until recently, PCVs were mostly available only in developed countries using a variety of dosing schedules. As more lower income countries make decisions to introduce PCV into their national immunization prog...
متن کاملSystematic Review of the Effect of Pneumococcal Conjugate Vaccine Dosing Schedules on Vaccine-type Invasive Pneumococcal Disease Among Young Children
BACKGROUND Pneumococcal conjugate vaccines (PCV) are being implemented globally using a variety of different schedules. The optimal schedule to maximize protection of vaccinated children against vaccine-type invasive pneumococcal disease (VT-IPD) is not known. METHODS To assess the relative benefit of various PCV dosing schedules, we conducted a systematic review of studies published in Engli...
متن کاملWhy Do We Need a Systematic Review of Pneumococcal Conjugate Vaccine Dosing Schedules?
Supplement I t is well known that Streptococcus pneumoniae remains a leading cause of childhood mortality; in 2008, it was estimated to be responsible for over 500,000 deaths in children aged 1–59 months. 1 It is also known that the pneumococcus is a cause of significant morbidity and mortality among those younger and older than the 1-to 59-month age group, 2,3 although prevention of disease in...
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ژورنال
عنوان ژورنال: Pediatric Infectious Disease Journal
سال: 2014
ISSN: 0891-3668
DOI: 10.1097/inf.0000000000000076